Season 6: Episode 17, "Christian Troy II" Toward the very end of the series, Nip/Tuck proved-once again-that changing the narrative landscape of the series was rarely a good idea. mime who robs convenience stores? (We can’t make this stuff up, people.) Season 6: Episode 5, "Abigail Sullivan" While Sean, Annie, and Conor nearly escape the good doctor’s quickie marriage to serial killing anesthesiologist Teddy (played by Katee Sackhoff in Season 5, then Rose McGowan in Season 6), poor Matt has resorted to becoming a. Season 5: Episode 6, "Damien Sands" Like "Conor McNamara, 2026," this episode mostly steps outside the normal continuity of Nip/Tuck and plays out in the form of "Plastic Fantastic," a new reality show that Christian has convinced Sean to film. This episode attempts the latter-and shows the audience where the characters would be a decade from today, to pretty much non-memorable effect. Season 4: Episode 11, "Conor McNamara, 2026" There are two things that are hard for even the most innovative of shows to pull off well: dream sequences and flash-forwards. Season 4: Episode 9, "Liz Cruz" Liz Cruz (Roma Maffia), McNamara/Troy's trusty anesthesiologist and longtime conscience, is still recovering from a kidney transplant-damn those organ thieving prostitutes!-when she books a bit of liposuction with the doctors to impress her new girlfriend, Poppy (Alanis Morissette), who clearly sees much more room for physical improvement. To do it, he takes him to a strip club where he barters a lap dance in exchange for a breast reduction. Season 4: Episode 2, "Blue Mondae" Christian attempts to turn his new patient, a young gay man whose lover is paying to make him look more distinguished, straight. Desperate for cash, the doctors agree to reassemble the bodies of several corpses that have been mutilated to create one female body for necrophilic-and, it turns out, incestuous-purposes. Season 3: Episode 6, "Frankenlaura" McNamara/Troy is hurting for business in the wake of Christian being arrested as a possible serial killer. That said, there are some clunker episodes throughout the series, including: Yet the same season features great episodes with Peter Dinklage as Marlowe Sawyer, manny to the McNamara’s newborn son, Conor. It’s a storyline and set of characters that are neatly disposed of and forgotten about once the season is over. Case in point: Season 4, which sees the arrival of Burt and Michelle Landau (Larry Hagman and Sanaa Lathan), who buy into the McNamara/Troy business, only to see Michelle be blackmailed by her former pimp/lover, James (Jacqueline Bisset), into turning the office into a den of organ thievery. But amidst the sometimes messy results, there are moments-and even full hours-of creative brilliance that make watching the series in its entirety worth the time and effort. Seasons/Episodes You Can Skip: Like facelifts, not every season of Nip/Tuck is perfectly executed. Over the course of six seasons, viewers faced an onslaught of bizarre storylines that included brushes with drug-dealing, organ-harvesting, porn-making, Scientology, and an unhinged wannabe talent agent who kills a rival with a teddy bear-making machine. Which makes it sound a lot more touchy-feely than it really is. The series touches on a number of taboo subjects that would still be considered a bit controversial today-including, on more than one occasion, pedophilia and incest-but at its heart, the series is about accepting people, including ourselves, with all of our flaws. In addition to being an immediate hit when it premiered in 2003, Nip/Tuck was also immediately controversial. Though it quickly becomes apparent that no one’s life is as perfect as it seems. Meanwhile, Sean is a dutiful family man: husband to his college sweetheart, Julia (Joely Richardson), and father to his children Matt (John Hensley) and Annie (Kelsey Batelaan). Christian, on the other hand, is in this business for the women when he’s not in surgery, he’s often out trolling the city’s nightlife scene for new patients. Like a hipper, and far more stomach-churning, version of House, the series sees the doctors perform your standard vanity procedures-boob jobs, liposuction, facelifts-but also paints them as innovators in their field, largely due to Sean’s medical expertise. The series begins its run in Miami, where college buddies-turned-medical partners Sean McNamara (Dylan Walsh) and Christian Troy (Julian McMahon) run one of the city’s most elite plastic surgery practices. WIRED Binge-Watching Guide: Halt and Catch Fire Arrow
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It Can Cater to Both your Scanning and Printing Needs.Not only can you reduce the picture size using the photocopier, but you can increase the same. One of the brilliant features enabled in a photocopier is that it can rearrange the size of your diagram, photograph and even texts. It Can Both Increase the Size of Your Document and Decrease the Same As Well.However, for a few pages, the printer is a cheaper alternative. For those who want to print several copies, you might want to turn to a photocopier supplier and get the finest quality photocopiers for your office. However, this is based on the number of data, pages and copies that you want to print. Printer: How the Photocopier Shares Differences with Printer in Terms of Cost?Ī lot of people think that printing multiple copies of a document using a printer is much cheaper than photocopying the same. The multifunction printers like a Canon printer are experts at handling regular office works like printing, faxing, copying, and scanning besides being a go-to machine which every office staff likes. The Printers are Great for Everyday Office Works The photocopiers besides being efficient are reliable too with more such unique features like hole punching, stapling, faxing and printing. The photocopiers are designed solely to cater to heavy-duty tasks and produce documents with finishing features like sorting and binding. When it comes to features, both devices have a lot of dissimilarities which makes them suitable for different purposes. Photocopier Are More Efficient Than Printers Printer: How They Differ From Each Other in Regards to Features? The higher version of the office printers is enabled with other distinctive features like fax, copier and scanner. The photocopier supplier is offering various advanced printers which not only support memory cards but also scanners and digital cameras. However, the printers on the other side are peripheral devices that produce digital data’s solid copies that are displayed on the screen. The Photocopiers rely on xerography technology, which in turn is defined by a dry process of image creation through toner and heat application to the paper. Photocopiers Resort Xerography Technology and Printers Creates Solid Copies of Digital Information Printer: How Do They Differ From Each Other in Terms of Functionalities? To make things simpler, here is all the information that you need for a photocopier and printer. Owing to such overlapping features of both the devices, you might get confused as to which machine to invest in. Given the advancement and improvement of technology, the photocopiers and printers are both being designed with almost the same features, given how the Canon printer and many more such printers come with the same features as photocopiers. While the primary function of a photocopier is to produce duplicate copies, a printer’s is used for printing copiers. But that costs coin, which has a bad habit of running out, so they join an underground fighting ring and bash their way to cash. After making some slight modifications, our Vox Machina d20 set has made its triumphant return! Celebrate the legendary heroes of Tal'Dorei with this d20 set based on our first campaign. The third series of the celebrated Vox Machina Origins comics, from Critical Role and Dark Horse Vox Machina enjoy a week in Westruun’s lap of luxury leading up to the Winter’s Crest Festival. Signs of brainstem affection like persistent hiccup, nausea or vomiting should explicitly be asked for as they are often attributed to other reasons and are therefore not reported spontaneously by the patient. In NMOSD and MOG-EM, most common symptoms are optic neuritis and longitudinally extensive transverse myelitis (LETM). To find all relevant publications, we did not restrict the year of publication however, most reports originate from the last 5 years. We used the search terms “neuromyelitis optica,” “neuromyelitis optica spectrum disorder,” “MOG,” aquaporin-4 antibodies,” “MRI,” “diagnostic criteria,” “therapy,” and combinations of these. To give an overview on diagnosis and treatment recommendations in NMOSD and MOG-EM, we here describe our own clinical experiences and give a review on the current literature using the Pubmed online database. To date, the relevance of MOG-Abs and their nosologic categorization is a topic of current discussion and under further investigation ( 47, 52, 53). Although ADEM can also be accompanied by MOG-Abs ( 51), in this manuscript we do not regard MOG-Ab positive patients with ADEM-phenotype as part of the “MOG-EM” due to their distinct clinical characteristics. Hereafter, we use the term “MOG-EM,” as it reflects the relevant symptoms of the disease and is used in several recent publications, e.g., ( 49). Various terms are used to describe the disease such as “MOG-antibody related disorder,” “MOG-associated disease,” “MOG antibody disease,” “MONEM” or “MOG-encephalomyelitis (MOG-EM)”( 40, 47– 50). Previous studies on NMOSD might have included patients with MOG-Abs and therefore overlapping features could have been reported in these studies. Although there are numerous overlaps in clinical presentation and imaging findings with NMOSD with and without AQP4-Ab, MOG-Ab-associated disease is more and more considered a disease entity in its own ( 47). According to the revised 2015 NMOSD diagnostic criteria ( 46), diseases with or without evidence of AQP4-Abs as well as disorders with MOG-Abs can be assigned to the NMO spectrum. MOG is a glycoprotein localized on the surface of the myelin sheath as well as of the cell body and processes of oligodendrocytes ( 44, 45). In the past, MOG-Abs were particularly described in acute disseminated encephalomyelitis (ADEM), an inflammatory CNS disorder that, if it has an pediatric onset, is mostly monophasic and has a favorable outcome in the majority of cases ( 42, 43). Recently, various publications described the detection of serum-Abs against myelin-oligodendrocyte-glycoprotein (MOG) in AQP4-Ab negative NMOSD patients including pediatric cohorts and few patients with MS ( 29– 41). Whether AQP4-Ab positive and AQP4-Ab negative diseases are varieties of the same disorder or rather reflect different disease entities is a topic of ongoing research ( 26– 28). In 20–30% of patients, depending on the assay used, AQP4-Abs are not detectable ( 24, 25). Women are disproportionately more often affected and, particularly in AQP4-seropositive patients, female to male-ratio can reach up to 10:1 ( 19, 22, 23). Disease onset ranges between 4 and 88 years with a mean age at onset of 39 years ( 18– 21). Patients without long-term immunosuppressive therapy have a worse prognosis with a higher mortality rate ( 17). Thus, in relapsing NMOSD, which account for approximately 80–85% of cases, neurologic deficits frequently accumulate during the disease course. Despite treatment, recovery from attacks is often incomplete and disease remission rarely occurs ( 15, 16). Patients also frequently suffer from burdensome symptoms like pain, headache, depression, fatigue, and sleep disorders ( 10– 14). In rarer cases, brainstem and brain involvement e.g., area postrema syndrome or diencephalic syndrome can occur ( 8, 9). In the majority of patients with NMOSD, autoantibodies (Abs) against the astrocyte aquaporin-4 (AQP4) water channel are detectable and patients typically suffer from recurrent attacks of severe optic neuritis or/and myelitis ( 3– 7). The French term “neuro-myélite optique aiguë,” which may be translated as “neuromyelitis optica acuta” was first used by Devic in 1894 ( 1, 2). Neuromyelitis optica spectrum disorders (NMOSD) are rare chronic inflammatory central nervous system diseases distinct from multiple sclerosis (MS). 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The pathological continuum of navicular stress fractures begins when the ‘microdamage’ exceeds the bone’s threshold (Bennell, Malcolm, Wark, et al., 1996). However, repetitive stress associated with failed bone remodelling can begin the pathological process resulting in stress reaction, stress fracture and subsequent complete fracture of the navicular (McCormick et al., 2011 Warden et al., 2006). Whilst, this is defined as the initial stage of the stress fracture continuum, no current evidence suggests intervention is required as bone has the ability to remodel and repair (Warden et al., 2006). Repetitive stress of a bone is naturally associated with ‘microdamage’ and is a normal phenomenon in humans (Bennell, Malcolm, Wark, & Brukner, 1996 Warden et al., 2006). Through repetitive bouts of mechanical load, potential for bone strain occurs (Warden, Burr, & Brukner, 2006). As a consequence, the maximum shear stresses are exerted through the central third of the navicular body (Gross & Nunley, 2014 Mann & Pedowitz, 2009). During foot-strike initially the navicular accepts force from first and second metatarsocuneiform joints, then medially sharing force with the talar head and finally lateral forces from the second metatarsal and middle cuneiform (Gross & Nunley, 2014). The navicular bone is anatomically located in a unique position that exposes it to various forces and an unusual vascular supply, leaving it vulnerable to overuse injury (Jones & Amendola, 2006 Mann & Pedowitz, 2009). However, we now know navicular stress fractures are one of the most common stress fracture sites in the body (Mann & Pedowitz, 2009), with evidence suggesting they comprise 14% to 25% of all stress fractures (Bennell, Malcolm, Thomas, Wark, & Brukner, 1996 Brukner, Bradshaw, Khan, White, & Crossley, 1996). Navicular stress fractures were first described by Towne and colleagues in 1970 and initially were thought to be rare (Jones & Amendola, 2006). As a result, patients presenting with this injury are classically running athletes (Gross & Nunley, 2014), with one study demonstrating 59% of navicular stress fractures are track and field athletes (Brukner et al., 1996). Navicular stress fractures are an overuse injury characterized by tenderness over the navicular bone which usually results from repetitive impact loading causing a reduction in its load-absorbing properties. It's awesome to have other like-minded clinicians put time into sharing their knowledge with others and contributing to Rayner & Smale. Recently Josh has been learning about navicular stress fractures, and for this blog, he shares his new knowledge about the causes, risk factors, pathophysiology and management of this condition. Teaching is another great passion of his and in the future Josh's hope is to help educate the next generation of clinicians. Over the past few years Josh has developed a great interest in spinal pathologies, particularly non-specific neck pain and is planning to one day further research for physiotherapists in this area. In 2015, Josh completed the graduate certificate of musculoskeletal physiotherapy at La Trobe University and is currently undertaking the masters program at La Trobe. Josh completed his undergraduate degree at Monash University in 2012 and has since been practicing at Physica. This week we are joined by Josh Farragher, Physiotherapist at Physica Spinal and Physiotherapy Clinic in Melbourne, Australia. |
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